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Image Search Results
Journal: Nature Communications
Article Title: High-resolution cryo-EM of the human CDK-activating kinase for structure-based drug design
doi: 10.1038/s41467-024-46375-9
Figure Lengend Snippet: a Chemical structure of CT7030. b Cryo-EM structure of CAK-bound CT7030. c In vitro kinase inhibition data of CT7030 compared with ICEC0942. Numbers in brackets indicate 95% confidence intervals for the IC 50 values (ND not determined). d , e Plots of the data underlying the values in a ( n = 2). Source data are provided as a Source Data file.
Article Snippet:
Techniques: Cryo-EM Sample Prep, In Vitro, Inhibition